AbstractIn this paper, we introduce the concept of tri-quasi hyperideal in Γ-semihyperring generalizing the classical ideal, left ideal, right ideal, bi-ideal, quasi ideal, interior ideal, bi-interior ideal, weak interior ideal, bi-quasi ideal, tri-ideal, quasi-interior ideal and bi- quasi-interior ideal of Γ-semihyperring and semiring. Furthermore, charecterizations of Γ-semihyperring, regular Γ-semihyperring and simple Γ-semihyperring with relative tri- quasi hyperideals are provided discussing the characteristics of Γ-semihyperring of relative tri-quasi hyperideals.